Glossary · The science

What does Endocannabinoid System stand for?

Endocannabinoid System: ECS

A biological system present in all mammals that plays a role in regulating pain, mood, appetite, sleep, and immune function. THC and CBD interact with this system to produce their effects.

Related terms

  • CBD (Cannabidiol)

    The second most studied cannabinoid. Non-intoxicating. Has anti-inflammatory, anxiolytic, anticonvulsant, and analgesic properties. Used in Epidyolex (licensed for epilepsy) and as a component in many unlicensed CBPMs.

  • THC (Tetrahydrocannabinol)

    The primary psychoactive compound in cannabis. Responsible for the "high" associated with recreational use. At controlled therapeutic doses, THC has analgesic, antiemetic, muscle-relaxant, and sleep-promoting effects. The main active compound in most CBPM flower and high-THC oil prescriptions.

  • Allodynia

    Pain caused by a stimulus that does not normally provoke pain, such as light touch or clothing against the skin. Common in neuropathic pain conditions.

  • Antiemetic

    A drug that prevents or treats nausea and vomiting. Cannabinoids, particularly THC and nabilone, have antiemetic properties used in chemotherapy-induced nausea.

  • Anxiolytic

    A medication or substance that reduces anxiety. CBD has well-documented anxiolytic properties.

This is a plain-language definition for general understanding, not medical or legal advice.

All 101 terms